Claire, who was 32 at the time, was last seen leaving the Seamus O’Donnell’s pub in St Nicholas Street, Bristol, on the evening of Wednesday 6 June, 2012. We suspect Claire was the victim of a crime and are treating her disappearance as suspicious.

Our key appeal points are below – can you help with any of the following?

- Were you in the Seamus O’Donnell’s pub on the night Claire was last seen – Wednesday 6 June, 2012? If you were and haven’t yet spoken to us, please do so now.

- Did you see a woman matching Claire’s description heading into Bristol city centre from the direction of St Nicholas Street after 11pm. You may have seen her elsewhere in Bristol on the same evening - if so, we want to speak to you. Claire is described as white, 5ft tall, of slim build, with shoulder-length brown hair, which was sometimes tied back in a ponytail.

Were you a friend or acquaintance of Claire? If you didn’t speak to police at the time she went missing, or since, now is the time.

- Has someone told you information about this case which may have sounded unusual or suspicious? Has anyone confided in you about what may have happened to Claire?